300 men with klinefelter syndrome to be tracked for decades in landmark study

NCT ID NCT07142135

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study will follow 300 men with Klinefelter syndrome (an extra X chromosome) who are treated at a Danish hospital. Researchers will collect medical records, scans, and blood samples to map how the condition affects growth, hormones, fertility, heart health, and mental well-being over time. The goal is to fill knowledge gaps and improve care for this often-underdiagnosed condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could lead to better guidelines for treating and monitoring Klinefelter syndrome, improving long-term health and quality of life for affected men.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may take years and might not change current care quickly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Klinefelter syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Copenhagen University Hospital, Rigshospitalet, Department of Growth and Reproduction

    Copenhagen, 2100, Denmark