New blood test could predict kidney transplant rejection before it happens

NCT ID NCT04727788

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a blood test that looks at gene activity to predict the risk of kidney transplant rejection. Researchers will follow 550 kidney transplant recipients to see if the test can identify those at risk for early rejection or long-term damage. The goal is to help doctors intervene sooner and improve transplant outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this blood test could help doctors identify kidney transplant patients at high risk for rejection early, allowing for personalized treatment.
What could go wrong
This is an observational study, not a treatment trial. The test may not be accurate enough for widespread use, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bologna University

    Bologna, Italy

  • Brescia University

    Brescia, Italy

  • CHU Grenoble Alpes Health Center

    Grenoble, France

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Henry Ford

    Detroit, Michigan, 48202, United States

  • Northwestern University

    Evanston, Illinois, 60611, United States

  • University Hospital Vall d'Hebron, Barcelona

    Barcelona, Spain

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • University of Maryland

    Baltimore, Maryland, 21201, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15261, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

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