Blood test may spare kidney transplant patients from painful biopsies
NCT ID NCT06406179
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a blood test that measures donor DNA (dd-cfDNA) can safely guide follow-up care for kidney transplant patients, potentially reducing the need for invasive biopsies. 500 adult kidney transplant recipients will be randomly assigned to standard care or a strategy where doctors use dd-cfDNA results to decide whether a biopsy is needed. The goal is to see if this approach maintains kidney function while avoiding unnecessary procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Donor-derived cell-free DNA (dd-cfDNA) blood test
What this could lead to
If successful, this could reduce the need for invasive biopsies in kidney transplant patients, making monitoring safer and more comfortable.
What could go wrong
This is a Phase 2-like trial with 500 participants, so results may not apply to all patients. The blood test may not catch all rejection cases, and some biopsies may still be needed.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP-HP - Hôpital Tenon
ACTIVE_NOT_RECRUITINGParis, France
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CHU Toulouse
NOT_YET_RECRUITINGToulouse, France
Contact Email: •••••@•••••
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Georges Pompidou European Hospital
ACTIVE_NOT_RECRUITINGParis, 75015, France
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Hopital Saint Louis
RECRUITINGParis, Île-de-France Region, 75010, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Necker-Enfants Malades
ACTIVE_NOT_RECRUITINGParis, 75015, France
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Hôpital de la Salpêtrière hôpital à Paris
RECRUITINGParis, Île-de-France Region, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••