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ICU kidney injury: does the pattern predict lasting damage?

NCT ID NCT05247502

Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers are studying adults who spend more than a day in intensive care to understand how acute kidney injury affects kidney health months later. The study tracks the occurrence and duration of kidney injury episodes during the ICU stay and measures kidney function at 3 and 12 months after hospitalization. The goal is to see whether specific features of acute kidney injury are linked to major kidney events, including chronic kidney disease, the need for dialysis, or death.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers link specific patterns of acute kidney injury to worse long-term kidney outcomes, doctors could identify high-risk ICU patients earlier and tailor monitoring or treatment after discharge.
What could go wrong
This is an observational study with a small number of participants, so it cannot prove cause and effect. The findings may not apply to all ICU patients, and tracking alone does not improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

10 people

The number who actually took part.

Started

Nov 2022

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The MAKI study will recruit a large population of ICU patients. Patients who are hospitalized for more than 24 hours in ICU will be eligible to participate in the study. The MAKE evaluation after different kind of Acute Kidney Injury (MAKI) study will be conducted in 4 ICUs in Clermont-Ferrand, France. All ICU units include both medical and surgical patient recruitment. The patients will be classified into 3 groups based on the occurrence of AKI and its duration: 1) patients without AKI during their stay, 2) patients who had a transient AKI episode (defined as recovery within 48 hours of onset), and 3) patients who had a persistent AKI episode during their stay.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who are hospitalized for more than 24 hours in ICU will be eligible to participate in the study. Exclusion Criteria: * patients who are younger than 18 years, * those who are pregnant, * those who have chronic extrarenal epuration before their admission to the ICU, * those who are admitted for kidney transplantation, * those under the safeguard of justice, and those who refuse to participate in the study.

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Conditions

The condition(s) this trial relates to.

acute kidney injury chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury Persistent acute renal failure Transient acute renal failure

Contacts and locations

Locations

  • CHU clermont-ferrand

    Clermont-Ferrand, France

  • Centre Jean-Perrin

    Clermont-Ferrand, France

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