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Can a kidney ultrasound scan warn of kidney damage after heart bypass surgery?

NCT ID NCT07821983

Diagnosis Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Acute kidney injury is a common complication after coronary artery bypass grafting. This observational study examines whether two measurements from kidney Doppler ultrasound, the renal augmented velocity index and the renal resistive index, can predict which patients will develop this injury. About 200 adults scheduled for elective isolated bypass surgery with cardiopulmonary bypass receive bilateral kidney ultrasound scans one day before surgery, within 60 minutes of intensive care unit admission, and 6 hours later. Researchers track who develops acute kidney injury within 7 days after surgery, using standard KDIGO criteria based on blood creatinine and urine output. The ultrasound results do not guide patient care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
renal Doppler ultrasonography, a kidney ultrasound scan
What this could lead to
If the ultrasound measurements prove reliable, doctors could one day flag patients at high risk of kidney injury right after bypass surgery and act earlier to protect their kidneys.
What could go wrong
This is a small, single-center observational study, so the ultrasound measurements may not predict kidney injury well enough to be useful, and the findings may not hold in other hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults scheduled for elective isolated on-pump coronary artery bypass grafting at Bursa Yuksek Ihtisas Training and Research Hospital who meet all eligibility criteria. Consecutive eligible patients will be approached before surgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Scheduled for elective isolated coronary artery bypass grafting with cardiopulmonary bypass (on-pump). * Able and willing to provide written informed consent. * Both kidneys present. * Adequate bilateral preoperative renal Doppler signal for study measurements. Exclusion Criteria: * Preoperative chronic dialysis or renal replacement therapy. * Urgent or emergency surgery. * Combined cardiac surgery, including valve, aortic, or another major additional procedure. * Off-pump coronary artery bypass grafting or conversion of the planned surgical technique. * Clinically significant rhythm disturbance preventing acquisition of three interpretable cardiac cycles. * Renal transplant, solitary kidney, significant renal artery stenosis, previous renal artery intervention, hydronephrosis, or other relevant renal vascular or structural disease. * Inadequate bilateral preoperative renal Doppler examination. * Withdrawal of consent.

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Conditions

The condition(s) this trial relates to.

acute kidney injury coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury Coronary artery disease

How to take part

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  2. The official record

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Contacts and locations

Locations

  • Bursa Yuksek Ihtisas Training and Research Hospital

    Bursa, Bursa, Turkey (Türkiye)

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