Can a High-Fat diet help pelvic cancer patients during radiation?
NCT ID NCT05938322
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether people with rectal cancer can stick to a ketogenic diet (very low carbs, high fat) during chemoradiation. About 194 participants will be randomly assigned to either the ketogenic diet or a standard Mediterranean diet for 5 weeks. The main goal is to see how well they follow the diet, and researchers will also check changes in body fat and muscle mass.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketogenic diet
What this could lead to
If successful, this could show that a ketogenic diet is a practical option for patients undergoing pelvic cancer radiotherapy, potentially improving nutritional status and body composition.
What could go wrong
This is a small, early-stage study focused on diet adherence, not on cancer outcomes. Results may not apply to all patients, and the strict diet may be hard to follow for some.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Universitario Agostino Gemelli, IRCCS
RECRUITINGRome, Italy