Could a High-Fat, Low-Carb diet ease schizophrenia?
NCT ID NCT05968638
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a ketogenic diet—low in carbs, high in fat—can reduce symptoms in people with schizophrenia or schizoaffective disorder. Fifty adults will be randomly assigned to either the ketogenic diet or a regular diet for several weeks. Researchers will measure changes in psychiatric symptoms using a standard rating scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketogenic diet
What this could lead to
If it works, this could point toward a dietary approach to help manage schizophrenia symptoms alongside standard treatments.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply widely. The diet is hard to stick to and may cause side effects like fatigue or nutrient imbalances.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Maryland Psychiatric Research Center (MPRC) Treatment Research Program (TRP)
Catonsville, Maryland, 21228, United States