Could a High-Fat diet lift bipolar depression?

NCT ID NCT07121894

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a strict high-fat, low-carbohydrate (ketogenic) diet can help ease depression in people with bipolar disorder. Thirty adults aged 18 to 50 with bipolar I or II will follow the diet for 8 weeks while researchers track mood changes and heart health. The goal is to see if this diet is a practical and effective add-on treatment.

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Conditions

The condition(s) this trial relates to.

bipolar depression bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact