Could a High-Fat diet lift bipolar depression?

NCT ID NCT07121894

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a strict high-fat, low-carbohydrate (ketogenic) diet can help ease depression in people with bipolar disorder. Thirty adults aged 18 to 50 with bipolar I or II will follow the diet for 8 weeks while researchers track mood changes and heart health. The goal is to see if this diet is a practical and effective add-on treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

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