Can a 4-Week Low-Carb diet make liver surgery safer?

NCT ID NCT05884723

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a 4-week ketogenic diet before liver surgery can reduce fat in the liver and lower the need for blood transfusions. About 124 adults with fatty liver and colorectal cancer that spread to the liver will either follow the diet or get standard dietary advice. The goal is to see if the diet makes surgery safer by reducing liver fat and bleeding risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketogenic diet (very low carbohydrate, high fat, moderate protein)

What this could lead to

If successful, this diet could become a standard short-term preparation to make liver surgery safer for patients with fatty liver.

What could go wrong

This is an early-stage trial with 124 participants, so results may not apply to everyone. The diet is strict and may be hard to follow, and it is not a treatment for the underlying liver disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fatty liver disease metabolic dysfunction-associated steatotic liver disease metastasis from malignant tumor of colon

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • London Health Sciences Centre/Western University

    RECRUITING

    London, Ontario, N6A 5A5, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••