Can a 4-Week Low-Carb diet make liver surgery safer?
NCT ID NCT05884723
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a 4-week ketogenic diet before liver surgery can reduce fat in the liver and lower the need for blood transfusions. About 124 adults with fatty liver and colorectal cancer that spread to the liver will either follow the diet or get standard dietary advice. The goal is to see if the diet makes surgery safer by reducing liver fat and bleeding risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ketogenic diet (very low carbohydrate, high fat, moderate protein)
- What this could lead to
- If successful, this diet could become a standard short-term preparation to make liver surgery safer for patients with fatty liver.
- What could go wrong
- This is an early-stage trial with 124 participants, so results may not apply to everyone. The diet is strict and may be hard to follow, and it is not a treatment for the underlying liver disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
London Health Sciences Centre/Western University
RECRUITINGLondon, Ontario, N6A 5A5, Canada
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