Could a keto drink lift depression? new trial tests brain effects

NCT ID NCT06263660

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a keto-like supplement, taken as a drink three times daily for 8 weeks, changes brain activity in people with moderate to severe depression. Researchers will use brain scans to compare the supplement to a placebo in 75 adults. The goal is to see if the supplement affects how the brain responds to positive and negative experiences.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

keto-like supplement

What this could lead to

If it works, this could point toward a new dietary supplement to help ease depression symptoms by altering brain responses.

What could go wrong

This is an early phase 2 trial with only 75 people, so results may not apply widely. The supplement may show no benefit over placebo, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Laureate Institute for Brain Research

    RECRUITING

    Tulsa, Oklahoma, 74136, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••