Heart surgery anesthesia showdown: can ketamine shield kidneys better than propofol?
NCT ID NCT05268562
First seen Jun 26, 2026 · Last updated Jul 14, 2026 · Updated 3 times
Summary
This study tests whether using ketamine or propofol for anesthesia at the start of heart surgery affects the risk of acute kidney injury. Researchers will enroll 200 adults undergoing complex heart surgery with a heart-lung machine. The goal is to see which drug leads to fewer kidney problems and better stability during surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketamine and propofol
- What this could lead to
- If ketamine proves better, it could become the preferred anesthetic for heart surgery to reduce kidney damage.
- What could go wrong
- This is a single-center Phase 4 trial with 200 participants, so results may not apply broadly. The study is active but not recruiting, and findings may show no difference between the drugs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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