Heart surgery anesthesia showdown: can ketamine shield kidneys better than propofol?
NCT ID NCT05268562
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using ketamine or propofol for anesthesia at the start of heart surgery affects the risk of acute kidney injury. Researchers will enroll 200 adults undergoing complex heart surgery with a heart-lung machine. The goal is to see which drug leads to fewer kidney problems and better stability during surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine and propofol
What this could lead to
If ketamine proves better, it could become the preferred anesthetic for heart surgery to reduce kidney damage.
What could go wrong
This is a single-center Phase 4 trial with 200 participants, so results may not apply broadly. The study is active but not recruiting, and findings may show no difference between the drugs.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARDIAC SURGERY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States