Could ketamine help veterans with back pain and depression?
NCT ID NCT06419439
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing whether ketamine infusions, combined with a brief counseling session, can help veterans who have both chronic low back pain and depression. About 44 veterans will receive four ketamine infusions over two weeks, and some will also get a short behavioral intervention. The goal is to see if this approach is feasible, safe, and acceptable, and to measure changes in pain interference and mood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine hydrochloride
What this could lead to
If it works, this could point toward a new treatment option that eases both pain and depression in veterans.
What could go wrong
This is a small, early pilot study with only 44 participants, so results may not apply widely. Ketamine can cause side effects like dizziness or dissociation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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VA Ann Arbor Healthcare System, Ann Arbor, MI
RECRUITINGAnn Arbor, Michigan, 48105-2303, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact