Ketamine shows promise for Hard-to-Treat depression in new brain study

NCT ID NCT06668571

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 32 times

Summary

This study tests whether a single dose of intravenous ketamine can rapidly reduce depression symptoms in 30 adults with treatment-resistant depression. Researchers will measure changes in key brain chemicals (GABA and glutamate) using brain scans and blood tests. The goal is to understand how ketamine works in the brain to improve symptoms within 24 hours.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

Conditions

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