Ketamine infusions show promise for maintaining relief in stubborn bipolar depression
NCT ID NCT05339074
First seen Sep 30, 2025 · Last updated May 13, 2026 · Updated 32 times
Summary
This study looked at whether repeated low-dose ketamine infusions could help people with treatment-resistant bipolar depression keep feeling better over 12 weeks. Forty-one adults who had already responded to an initial course of ketamine received up to six more infusions on a flexible schedule. The goal was to see if the treatment could maintain antidepressant effects and improve quality of life while being safe and well-tolerated.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Ontario Shores Centre for Mental Health Sciences
Whitby, Ontario, L1N 5S9, Canada
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Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
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Toronto Western Hospital
Toronto, Ontario, M5T 2S8, Canada
Conditions
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