New oral drug aims to slow Alzheimer's in its earliest stages

NCT ID NCT07027072

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests an experimental oral drug called KDS2010 in people with mild cognitive impairment or mild dementia due to Alzheimer's disease. Participants take either a low dose, a higher dose, or a placebo daily for 24 weeks. Researchers measure changes in memory, thinking, and daily living skills, along with blood and spinal fluid biomarkers, to see if the drug can slow disease progression.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
KDS2010
What this could lead to
If effective, KDS2010 could slow memory loss and daily function decline in early Alzheimer's, offering a new oral treatment option.
What could go wrong
This is an early Phase 2a dose-finding study with only 114 people. It may fail to show benefit or have side effects not yet seen in Phase 1.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ajou University Hospital

    RECRUITING

    Suwon, Gyeonggi-do, 16499, South Korea

  • Asan Medical Center

    RECRUITING

    Seoul, Seoul, 05505, South Korea

  • Chonnam National Unversity Hospital

    RECRUITING

    Gwangju, Gwangju, 61469, South Korea

  • Gachon University Gil Medical Center

    RECRUITING

    Incheon, Incheon, 21565, South Korea

  • Hanyang University Guri Hospital

    RECRUITING

    Guri-si, Gyeonggi-do, 11923, South Korea

  • Hanyang University Seoul Hospital

    RECRUITING

    Seoul, Seoul, 04763, South Korea

  • Konkuk University Medical Center

    RECRUITING

    Seoul, Seoul, 05030, South Korea

  • The Catholic University of Korea St. Vincent's Hospital

    RECRUITING

    Suwon, Gyeonggi-do, 16247, South Korea

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