Kava extract tested as a natural stress reliever for overworked nurses

NCT ID NCT06177535

First seen Jun 24, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This Mayo Clinic study is testing whether a daily kava supplement can lower stress hormones and reduce burnout in 200 surgical nurses. Participants take either kava extract or a placebo for a set period, and researchers measure changes in cortisol levels and burnout scores. The goal is to see if this natural supplement offers a safe, accessible way to support mental health in demanding healthcare jobs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Kava extract (kavalactones)
What this could lead to
If it works, this could point toward a natural supplement to help manage stress and burnout in high-pressure jobs.
What could go wrong
This is an early-stage study with no phase, so results are uncertain. Kava has known liver safety concerns, and the effect on burnout may be small or no different from placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic Minnesota

    Rochester, Minnesota, 55905, United States

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