Massive study seeks to unlock the secrets of Crohn's and colitis
NCT ID NCT01169207
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This long-running study at Johns Hopkins aims to identify the genetic and environmental factors that cause inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers are enrolling 2,500 participants — including patients, their family members, and healthy volunteers — to compare DNA and lifestyle data. The goal is to better understand why IBD develops, especially in families, which could lead to improved prevention or treatment in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could uncover genetic and environmental triggers for IBD, pointing toward better prevention or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It may take years to yield actionable results, and findings may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Johns Hopkins University
Baltimore, Maryland, 21231, United States