Massive study seeks to unlock the secrets of Crohn's and colitis

NCT ID NCT01169207

Ongoing Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This long-running study at Johns Hopkins aims to identify the genetic and environmental factors that cause inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers are enrolling 2,500 participants — including patients, their family members, and healthy volunteers — to compare DNA and lifestyle data. The goal is to better understand why IBD develops, especially in families, which could lead to improved prevention or treatment in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could uncover genetic and environmental triggers for IBD, pointing toward better prevention or treatment strategies.
What could go wrong: This is an observational study, not a treatment trial. It may take years to yield actionable results, and findings may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFLAMMATORY BOWEL DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLAMMATORY BOWEL DISEASE

Contacts and locations

Locations

Johns Hopkins University

Baltimore, Maryland, 21231, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.