New kidney drug interaction study launches in healthy volunteers

NCT ID NCT07181265

Not yet recruiting Knowledge-focused Sponsor: Jemincare Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-stage study tests how a new drug called JMKX003142 interacts with two common medications—amiodarone (for heart rhythm) and febuxostat (for gout)—in 48 healthy Chinese adults. Participants will take the drugs in sequence to measure how their bodies process them. The goal is to gather safety and dosing information, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

JMKX003142

What this could lead to

If successful, this study could help determine safe dosing of JMKX003142 when taken with other common drugs, supporting future trials for polycystic kidney disease.

What could go wrong

This is an early Phase 1 study in healthy volunteers, not patients. It only measures drug levels, not effectiveness. Results may not predict real-world outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal dominant polycystic kidney disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.