Lupus pain relief on the horizon? new drug shows promise in trial

NCT ID NCT03093402

First seen May 07, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This study tested a drug called JBT-101 (lenabasum) in 109 adults with lupus who had active joint pain. The goal was to see if it could reduce pain better than a placebo over 84 days. Participants took the drug by mouth and reported their daily pain levels. The study is complete, and results help understand if this approach can ease lupus symptoms without suppressing the immune system.

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Contacts and locations

Locations

  • Bronx-Lebanon Hospital Center: Division of Rheumatology

    The Bronx, New York, 10457, United States

  • Columbia University Medical Center: Department of Medicine, Division of Rheumatology

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Emory University: Division of Rheumatology

    Atlanta, Georgia, 30322, United States

  • Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases

    Manhasset, New York, 11030, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • MetroHealth Medical Center

    Cleveland, Ohio, 44109, United States

  • New York University Langone Medical Center: Department of Medicine, Division of Rheumatology

    New York, New York, 10016, United States

  • Penn State MS Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • UCLA Medical Center: Division of Rheumatology

    Los Angeles, California, 90095, United States

  • University of California San Diego School of Medicine: Division of Rheumatology, Allergy and Immunology

    La Jolla, California, 92093, United States

  • University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center

    San Francisco, California, 94143, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh Medical Center: Division of Rheumatology and Clinical Immunology

    Pittsburgh, Pennsylvania, 15217, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.