New heart valve fix without open surgery could change care for leaky aortic valve patients
NCT ID NCT07453407
First seen Mar 16, 2026 · Last updated May 12, 2026 · Updated 4 times
Summary
This study compares a newer, less invasive procedure called transcatheter aortic valve replacement (TAVR) using the J-VALVE system to traditional open-heart surgery for people with severe aortic regurgitation (a leaky heart valve). About 1,250 adults aged 65 and older with symptoms or signs of heart strain will be enrolled. The goal is to see if TAVR is as safe and effective as surgery in reducing death, stroke, and repeat hospital stays.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Anzhen Hospital Affiliated to Capital Medical University
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cheng Hsin General Hospital
NOT_YET_RECRUITINGTaibei, Taiwan, 100-116, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fuwai Hospital, Chinese Academy of Medical Sciences
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guangdong Provincial People's Hospital
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nanjing First Hospital
NOT_YET_RECRUITINGNanjing, Jiangsu, 210000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Taiwan University Hospital
NOT_YET_RECRUITINGTaibei, Taiwan, 100116, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Prince of Wales Hospital
NOT_YET_RECRUITINGHong Kong, Hong Kong, 999077, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Queen Mary Hospital
NOT_YET_RECRUITINGHong Kong, Hong Kong, 999077, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital, Zhejiang University School of Medicine
NOT_YET_RECRUITINGHangzhou, Zhejiang, 310000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310009, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xijing Hospital affiliated to Air Force Medical University
NOT_YET_RECRUITINGXi'an, Shaanxi, 710000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhongshan Hospital, Fudan University
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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