AORTIC VALVE INSUFFICIENCY
Clinical trials for AORTIC VALVE INSUFFICIENCY explained in plain language.
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Heart valve showdown: Less-Invasive procedure vs. open surgery
Disease control Recruiting nowThis large study aims to find out which of two procedures is better for treating severe aortic regurgitation, a condition where a heart valve leaks. It will compare a newer, less-invasive procedure (TAVR) with traditional open-heart surgery (SAVR) in 1,250 patients aged 65 and ol…
Matched conditions: AORTIC VALVE INSUFFICIENCY
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for heart pump patients with failing valves
Disease control Recruiting nowThis study is testing a new, less invasive heart valve replacement procedure for patients who have mechanical heart pumps (LVADs) and develop leaky aortic valves. The procedure uses a device called the JenaValve Trilogy system, which is inserted through blood vessels without open…
Matched conditions: AORTIC VALVE INSUFFICIENCY
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New Valve-in-Valve procedure aims to help High-Risk heart patients
Disease control Recruiting nowThis study is testing a new, less invasive heart valve called the SAPIEN X4. It is for people whose previous surgical valve replacement is now failing and who are at high risk for another open-heart surgery. Doctors will place the new valve inside the old one using a catheter thr…
Matched conditions: AORTIC VALVE INSUFFICIENCY
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Pioneering trial tests less invasive fix for leaky heart valves
Disease control Recruiting nowThis study aims to see if a new, less invasive procedure to replace a leaky aortic heart valve is as safe and effective as traditional open-heart surgery. It will involve over 1,000 patients with significant aortic regurgitation, where blood leaks backward into the heart. Researc…
Matched conditions: AORTIC VALVE INSUFFICIENCY
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Massive 10,000-Patient study tracks heart valve replacement outcomes
Knowledge-focused Recruiting nowThis study is collecting information about how patients do long-term after receiving a TAVR heart valve replacement procedure. It will follow 10,000 patients from multiple countries to see how they fare over time. The goal is to understand real-world outcomes, complications, and …
Matched conditions: AORTIC VALVE INSUFFICIENCY
Sponsor: Duk-Woo Park, MD • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC