Which IVF protocol works best for PCOS? new trial aims to find out

NCT ID NCT07394530

Recruiting now Disease control Sponsor: Hanoi General Hospital (Vietnam) Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common ovarian stimulation protocols used during IVF in women with polycystic ovary syndrome (PCOS). The PPOS protocol uses a progestin hormone to suppress ovulation, while the antagonist protocol uses a different drug. Researchers will track which method leads to more ongoing pregnancies at 12 weeks. The trial plans to enroll 400 women aged 18–40 with PCOS who are undergoing IVF.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Progestin (PPOS) and GnRH antagonist (for ovarian stimulation during IVF)
What this could lead to: If one protocol proves better, it could improve pregnancy success rates for women with PCOS undergoing IVF.
What could go wrong: This is a single-center study in Vietnam, so results may not apply to all populations. The trial is not blinded, which could introduce bias.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

female infertility polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FEMALE INFERTILITY POLYCYSTIC OVARY SYNDROME (PCOS)

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Hanoi General Hospital
RECRUITING

Hanoi, Hanoi, 10000, Vietnam

Contact Phone: •••-•••-•••• Email: •••••@•••••

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