New injection could shrink nasal polyps without surgery

NCT ID NCT07484230

Not yet recruiting Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests itepekimab, an injected antibody, in 20 Japanese adults with chronic sinusitis and nasal polyps that are not well-controlled despite surgery or steroids. The study measures changes in polyp size and nasal congestion over 52 weeks. It aims to see if the drug is safe and effective as a standalone treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

itepekimab (a monoclonal antibody injection)

What this could lead to

If it works, it could offer a new treatment option for people with nasal polyps that are not controlled by current therapies.

What could go wrong

This is a small, early-stage Phase 3 trial with only 20 participants, so results may not apply to everyone. The drug may not work better than placebo or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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