New shot aims to shrink stubborn nasal polyps

NCT ID NCT06834347

Summary

This study is testing a new injectable medicine called itepekimab for adults whose chronic sinusitis and nasal polyps are not well-controlled by standard nasal sprays. Over 200 participants will receive either the new medicine or a placebo for one year, in addition to their usual spray, to see if it safely reduces polyp size and congestion. The goal is to see if this treatment can better control the disease and potentially reduce the need for steroids or surgery.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ASST Santi Paolo e Carlo-Presidio Ospedale San Paolo-Site Number : 3800006

    RECRUITING

    Milan, Milano, 20142, Italy

    Contact Email: •••••@•••••

    Contact

  • Advanced Research Associates (ARA) Professionals- Site Number : 8400011

    RECRUITING

    Miami, Florida, 33176, United States

  • Alamo ENT Associates- Site Number : 8400065

    RECRUITING

    San Antonio, Texas, 78258, United States

  • Azienda Ospedale - Università Padova-Site Number : 3800008

    RECRUITING

    Padua, Padova, 35128, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Universitaria Careggi-Site Number : 3800011

    RECRUITING

    Florence, Firenze, 50134, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliero-Universitaria di Ferrara-Site Number: 3800004

    RECRUITING

    Cona, Ferrara, 44124, Italy

    Contact Email: •••••@•••••

    Contact

  • Breathe Clear Institute of Sinus and Allergy Relief- Site Number : 8400040

    RECRUITING

    Torrance, California, 90503, United States

  • Centro Internacional de Pesquisa Clínica (CIPES)- Site Number : 0760005

    RECRUITING

    São José dos Campos, São Paulo, 12230-001, Brazil

  • Deaconess Clinic Allergy East- Site Number : 8400056

    RECRUITING

    Evansville, Indiana, 47715, United States

  • ENT Associates of Texas - McKinne- Site Number : 8400062

    RECRUITING

    McKinney, Texas, 75070, United States

  • Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400046

    RECRUITING

    Norfolk, Virginia, 23510, United States

  • Emory University School of Medicine- Grady Campus- Site Number : 8400047

    RECRUITING

    Atlanta, Georgia, 30303, United States

  • Essential Medical Research- Site Number : 8400066

    RECRUITING

    Tulsa, Oklahoma, 74137, United States

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Site Number: 3800002

    RECRUITING

    Rome, Roma, 00168, Italy

    Contact Email: •••••@•••••

    Contact

  • Hospital Israelita Albert Einstein- Site Number : 0760001

    RECRUITING

    São Paulo, 05651-901, Brazil

  • Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto- Site Number : 0760002

    RECRUITING

    Ribeirão Preto, São Paulo, 14049-900, Brazil

  • Houston Methodist Hospital- Site Number : 8400054

    RECRUITING

    Houston, Texas, 77030, United States

  • IRCCS Ospedale Policlinico San Martino-Site Number : 3800013

    RECRUITING

    Genoa, Genova, 16132, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Investigational Site Number : 0320001

    RECRUITING

    Buenos Aires, 1425, Argentina

  • Investigational Site Number : 0320002

    RECRUITING

    La Plata, Buenos Aires, 1900, Argentina

  • Investigational Site Number : 0320003

    RECRUITING

    Mendoza, 5500, Argentina

  • Investigational Site Number : 0320004

    RECRUITING

    Rosario, Santa Fe Province, 2000, Argentina

  • Investigational Site Number : 0320005

    RECRUITING

    Buenos Aires, 1638, Argentina

  • Investigational Site Number : 0400001

    RECRUITING

    Vienna, 1090, Austria

  • Investigational Site Number : 0400002

    RECRUITING

    Linz, 4010, Austria

  • Investigational Site Number : 0400005

    RECRUITING

    Graz, 8036, Austria

  • Investigational Site Number : 1240001

    RECRUITING

    Québec, Quebec, G1V 4G5, Canada

  • Investigational Site Number : 1240002

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • Investigational Site Number : 1240005

    RECRUITING

    London, Ontario, N6A 4V2, Canada

  • Investigational Site Number : 1520001

    RECRUITING

    Santiago, Reg Metropolitana de Santiago, 8207257, Chile

  • Investigational Site Number : 1520002

    RECRUITING

    Santiago, Reg Metropolitana de Santiago, 7500692, Chile

  • Investigational Site Number : 1520003

    RECRUITING

    Talca, Maule Region, 3465584, Chile

  • Investigational Site Number : 1520004

    RECRUITING

    Lo Barnechea, Reg Metropolitana de Santiago, 7691236, Chile

  • Investigational Site Number : 1520005

    RECRUITING

    Viña del Mar, Región de Valparaíso, 2540364, Chile

  • Investigational Site Number : 1520006

    RECRUITING

    Valdivia, Los Ríos Region, 5110683, Chile

  • Investigational Site Number : 2460002

    RECRUITING

    Kuopio, 70210, Finland

  • Investigational Site Number : 2460003

    RECRUITING

    Helsinki, 00130, Finland

  • Investigational Site Number : 2460004

    RECRUITING

    Helsinki, 00290, Finland

  • Investigational Site Number : 2760001

    RECRUITING

    Tübingen, 72076, Germany

  • Investigational Site Number : 2760002

    RECRUITING

    Münster, 48149, Germany

  • Investigational Site Number : 2760003

    RECRUITING

    Würzburg, 97080, Germany

  • Investigational Site Number : 2760004

    RECRUITING

    Berlin, 10117, Germany

  • Investigational Site Number : 2760005

    RECRUITING

    Wiesbaden, 65205, Germany

  • Investigational Site Number : 3480001

    RECRUITING

    Pécs, 7621, Hungary

  • Investigational Site Number : 3480002

    RECRUITING

    Budapest, 1046, Hungary

  • Investigational Site Number : 3480003

    RECRUITING

    Nyíregyháza, 4400, Hungary

  • Investigational Site Number : 3480004

    RECRUITING

    Debrecen, 4032, Hungary

  • Investigational Site Number : 3760004

    RECRUITING

    Kefar Sava, 4428164, Israel

  • Investigational Site Number : 3760005

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Investigational Site Number : 3760007

    RECRUITING

    Haifa, 3436212, Israel

  • Investigational Site Number : 3760009

    RECRUITING

    Tel Aviv, 6423906, Israel

  • Investigational Site Number : 3920001

    RECRUITING

    Fukuoka, 812-0053, Japan

  • Investigational Site Number : 3920002

    RECRUITING

    Odawara, Kanagawa, 250-8558, Japan

  • Investigational Site Number : 3920003

    RECRUITING

    Kumamoto, 860-0814, Japan

  • Investigational Site Number : 3920004

    RECRUITING

    Narita, Chiba, 286-8520, Japan

  • Investigational Site Number : 3920005

    RECRUITING

    Suwa, Nagano, 392-0027, Japan

  • Investigational Site Number : 3920006

    RECRUITING

    Fukui, 910-1104, Japan

  • Investigational Site Number : 3920008

    RECRUITING

    Tokyo, 153-8515, Japan

  • Investigational Site Number : 3920009

    RECRUITING

    Isehara, Kanagawa, 259-1193, Japan

  • Investigational Site Number : 3920010

    RECRUITING

    Ichikawa, Chiba, 272-0143, Japan

  • Investigational Site Number : 3920011

    RECRUITING

    Hiroshima, 734-0004, Japan

  • Investigational Site Number : 3920012

    RECRUITING

    Kusatsu, Shiga, 525-0066, Japan

  • Investigational Site Number : 3920013

    RECRUITING

    Niigata, 951-8520, Japan

  • Investigational Site Number : 3920014

    RECRUITING

    Yokohama, Kanagawa, 236-0037, Japan

  • Investigational Site Number : 4100001

    RECRUITING

    Seoul, Seoul-teukbyeolsi, 07061, South Korea

  • Investigational Site Number : 4100002

    RECRUITING

    Seoul, Seoul-teukbyeolsi, 06351, South Korea

  • Investigational Site Number : 4100003

    RECRUITING

    Seoul, Seoul-teukbyeolsi, 03080, South Korea

  • Investigational Site Number : 4100004

    RECRUITING

    Seoul, Seoul-teukbyeolsi, 03722, South Korea

  • Investigational Site Number : 4100005

    RECRUITING

    Cheonan-Si, Chungcheongnam-do, 31116, South Korea

  • Investigational Site Number : 4100006

    RECRUITING

    Seoul, 02841, South Korea

  • Investigational Site Number : 4100008

    RECRUITING

    Incheon, Incheon-gwangyeoksi, 21565, South Korea

  • Investigational Site Number : 4100009

    RECRUITING

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Investigational Site Number : 4840003

    RECRUITING

    Durango, 34000, Mexico

  • Investigational Site Number : 4840004

    RECRUITING

    Chihuahua City, 31000, Mexico

  • Investigational Site Number : 5280002

    RECRUITING

    Leiderdorp, 2353 GA, Netherlands

  • Investigational Site Number : 5280004

    RECRUITING

    Alkmaar, 1815 JD, Netherlands

  • Investigational Site Number : 6160001

    RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 53-149, Poland

  • Investigational Site Number : 6160002

    RECRUITING

    Warsaw, Masovian Voivodeship, 00-909, Poland

  • Investigational Site Number : 6160003

    RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-756, Poland

  • Investigational Site Number : 6160004

    RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 53-301, Poland

  • Investigational Site Number : 6160005

    RECRUITING

    Lublin, Lublin Voivodeship, 20-363, Poland

  • Investigational Site Number : 6160006

    RECRUITING

    Krakow, Lesser Poland Voivodeship, 31-513, Poland

  • Investigational Site Number : 6200001

    RECRUITING

    Santa Maria da Feira, 4520-211, Portugal

  • Investigational Site Number : 6200002

    RECRUITING

    Porto, 3814-501, Portugal

  • Investigational Site Number : 6200003

    RECRUITING

    Guimarães, 4800-055, Portugal

  • Investigational Site Number : 6200004

    RECRUITING

    Matosinhos Municipality, 4464-513, Portugal

  • Investigational Site Number : 7240001

    RECRUITING

    Majadahonda, Madrid, 28222, Spain

  • Investigational Site Number : 7240002

    RECRUITING

    Barcelona, Catalunya [Cataluña], 08036, Spain

  • Investigational Site Number : 7240003

    RECRUITING

    Santiago de Compostela, A Coruña [La Coruña], 15706, Spain

  • Investigational Site Number : 7240004

    RECRUITING

    Jerez de la Frontera, Cádiz, 11407, Spain

  • Investigational Site Number : 7240005

    RECRUITING

    Zaragoza, 50009, Spain

  • Investigational Site Number : 7240006

    RECRUITING

    Seville, Sevilla, 41009, Spain

  • Investigational Site Number : 7240007

    RECRUITING

    Santiago de Compostela, A Coruña [La Coruña], 15702, Spain

  • Investigational Site Number : 7240008

    RECRUITING

    Barcelona, Barcelona [Barcelona], 08022, Spain

  • Investigational Site Number : 7240009

    RECRUITING

    Sabadell, 08208, Spain

  • Investigational Site Number : 7520001

    RECRUITING

    Solna, 171 64, Sweden

  • Investigational Site Number : 7520002

    RECRUITING

    Lund, 221 85, Sweden

  • Investigational Site Number : 7520004

    RECRUITING

    Stockholm, 114 86, Sweden

  • Investigational Site Number : 7920001

    RECRUITING

    Istanbul, 34093, Turkey (Türkiye)

  • Investigational Site Number : 7920002

    RECRUITING

    Istanbul, 34865, Turkey (Türkiye)

  • Investigational Site Number : 7920003

    RECRUITING

    Ankara, 06230, Turkey (Türkiye)

  • Investigational Site Number : 8260001

    RECRUITING

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Investigational Site Number : 8260002

    RECRUITING

    London, London, City of, NW1 2BU, United Kingdom

  • Investigational Site Number : 8260004

    RECRUITING

    Bradford, BD9 6RJ, United Kingdom

  • Investigational Site Number : 8260006

    RECRUITING

    Oxford, Oxfordshire, OX3 9DU, United Kingdom

  • Newport Native MD- Site Number : 8400031

    RECRUITING

    Newport Beach, California, 92663, United States

  • Northwell Health Physician Partners Rheumatology at Great Neck- Site Number : 8400028

    RECRUITING

    Great Neck, New York, 11021, United States

  • Orlando ENT Associates - Orlando- Site Number : 8400008

    RECRUITING

    Orlando, Florida, 32807, United States

  • Orso Health - Torrance - Hawthorne Boulevard- Site Number : 8400035

    RECRUITING

    Torrance, California, 90505, United States

  • Ospedale Bellaria-Site Number: 3800009

    RECRUITING

    Bologna, 40139, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Paradisus Med Research - Miami- Site Number : 8400009

    RECRUITING

    Miami, Florida, 33185, United States

  • SSM Health Saint Louis University Hospital- Site Number : 8400005

    RECRUITING

    St Louis, Missouri, 63104, United States

  • Sacramento Ear Nose & Throat - Roseville- Site Number : 8400064

    RECRUITING

    Roseville, California, 95661, United States

  • Sensa Health- Site Number : 8400038

    RECRUITING

    Los Angeles, California, 90006, United States

  • TEN20 Clinical Research - Dallas- Site Number : 8400015

    RECRUITING

    Dallas, Texas, 75244, United States

  • Treasure Valley Medical Research- Site Number : 8400063

    RECRUITING

    Boise, Idaho, 83706, United States

  • University of Chicago Medical Center- Site Number : 8400018

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Southern California (USC) / Keck Medicine of USC- Site Number : 8400037

    RECRUITING

    Arcadia, California, 91006, United States

Conditions

Explore the condition pages connected to this study.