Scientists heat up itch research to uncover how skin and brain talk
NCT ID NCT07395882
First seen Feb 10, 2026 · Last updated Jun 19, 2026 · Updated 20 times
Summary
This study aims to create a reliable, long-lasting itch model by combining heat with substances that cause itching, like histamine and cowhage. Researchers will measure how 28 healthy adults rate their itch and pain sensations, along with skin blood flow. The goal is to better understand the neurophysiology of itch, which could improve future research on itch treatments.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Center for Neuroplasticity and Pain Faculty of Medicine, Aalborg University Selma Lagerløfs Vej 249 9260 Gistrup, Denmark
Aalborg, Aalborg, 9620, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cowhage, histamine, and heat
What this could lead to
If successful, this could lead to better lab models for studying itch, helping future itch treatments.
What could go wrong
This is a small, early-stage observational study in healthy volunteers, not a treatment trial. Results may not apply to people with chronic itch conditions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.