Scientists probe itch and pain mysteries with histamine and cowhage

NCT ID NCT07247695

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand how people perceive itch and pain, and how factors like placebo (expecting relief) or nocebo (expecting worsening) affect those sensations. Thirty healthy volunteers will have itch triggered on their forearms using histamine (like an allergy test) and cowhage (a plant spicule). They will rate their itch and pain levels continuously. The results may help design better treatments for chronic itch and pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Histamine and cowhage (itch-inducing substances)

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg University

    RECRUITING

    Gistrup, 9260, Denmark

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••