New pacing technique aims to cut heart failure risk

NCT ID NCT07279870

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a newer pacing method called Conduction System Pacing (CSP) against standard right ventricular pacing in 1,260 adults with heart block. The goal is to see if CSP reduces heart failure events, hospitalizations, and need for additional procedures, while also improving quality of life and being cost-effective. Participants are randomly assigned to one of the two pacing approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Conduction System Pacing (CSP) procedure vs. standard Right Ventricular (RV) pacing procedure

What this could lead to

If CSP works better, it could become the new standard for pacing, reducing heart failure hospitalizations and improving daily life for people with heart block.

What could go wrong

This is a large trial but still early in testing. CSP is a newer, more complex procedure that may not always be successful or could have higher risks during implantation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrioventricular block

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APSS Trento - Ospedale S. Maria del Carmine di Rovereto

    NOT_YET_RECRUITING

    Trento, Italy

    Contact

  • ASST Grande Ospedale Metropolitano Niguarda

    NOT_YET_RECRUITING

    Milan, Italy

    Contact

  • Azienda Ospedal iera "Card. G. Panico"

    NOT_YET_RECRUITING

    Bari, Italy

    Contact

  • Azienda Ospedaliera Santa Maria della Misericordia

    NOT_YET_RECRUITING

    Perugia, Italy

    Contact

  • Azienda Ospedaliero-Univeritaria di Palermo - Policlinico Giaccone

    NOT_YET_RECRUITING

    Palermo, Italy

    Contact

  • Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara

    NOT_YET_RECRUITING

    Novara, Italy

    Contact

  • Azienda Ospedaliero-Universitaria Policlinico "G. Rodolico -San Marco"

    NOT_YET_RECRUITING

    Catania, Italy

    Contact

  • Azienda Ospedaliero-Universitaria di Ferrara

    RECRUITING

    Ferrara, Italy

    Contact

  • Azienda Ospedaliero-Universitaria di Parma

    NOT_YET_RECRUITING

    Parma, Italy

    Contact

  • Azienda Sanitaria locali di Asti Ospedale Cardinal Massaia

    NOT_YET_RECRUITING

    Novara, Italy

    Contact

  • Città delle Salute e della Scienza di Torino. Dipartimento Cardiovascolare e Toracico

    NOT_YET_RECRUITING

    Torino, Italy

    Contact

  • IRCCS AOUBO Policlinico di Sant'orsola

    RECRUITING

    Bologna, 40138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale di Rovigo Aulss 5 Polesana

    NOT_YET_RECRUITING

    Rovigo, Italy

    Contact

  • Policlinico Casilino

    NOT_YET_RECRUITING

    Roma, Italy

    Contact