New drug trial aims to ease skin hardening in rare autoimmune disease

NCT ID NCT04789850

Recruiting now Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether itacitinib is safe and effective for adults with systemic sclerosis, a disease that causes skin thickening and organ damage. About 74 participants with early or active disease will receive the drug or a placebo for one year. The main goal is to see if it reduces skin thickness, measured by a standard scoring method.

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Conditions

The condition(s) this trial relates to.

systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC SCLEROSIS

Contacts and locations

Locations

Ambroise Paré hospital
RECRUITING

Boulogne-Billancourt, 92100, France
Avicenne Hospital
RECRUITING

Bobigny, 93022, France
CH Amiens
RECRUITING

Amiens, 80000, France
CH Dax-Côte d'ARgent
RECRUITING

Dax, 40100, France
CH Le Mans
RECRUITING

Le Mans, 72037, France
CH Valenciennes
RECRUITING

Valenciennes, 59300, France
CH de Cornouaille
RECRUITING

Quimper, 29000, France
CHU Angers
RECRUITING

Angers, 49100, France
CHU Annecy
RECRUITING

Annecy, 74370, France
CHU Besançon
RECRUITING

Besançon, 25030, France
CHU Bordeaux
RECRUITING

Bordeaux, 33000, France
CHU Bordeaux
RECRUITING

Bordeaux, 33000, France
CHU Caen
RECRUITING

Caen, 14000, France
CHU Dijon
RECRUITING

Dijon, 21000, France
CHU Gabriel Montpied
RECRUITING

Clermont-Ferrand, 63000, France
CHU Grenoble
RECRUITING

Grenoble, 38700, France
CHU Grenoble
RECRUITING

Grenoble, 38700, France
CHU Lille
RECRUITING

Lille, 59000, France
CHU Limoges
RECRUITING

Limoges, 87000, France
CHU Lyon sud
RECRUITING

Lyon, 69310, France
CHU Montpellier - St Eloi Hospital
RECRUITING

Montpellier, 34090, France
CHU Montpellier - rhumatology
RECRUITING

Montpellier, 34090, France
CHU Nancy
RECRUITING

Nancy, 54035, France
CHU Nantes
RECRUITING

Nantes, 44093, France
CHU Poitiers
RECRUITING

Poitiers, 86021, France
CHU Rouen
NOT_YET_RECRUITING

Rouen, 76000, France
CHU Saint Etienne
RECRUITING

Saint-Etienne, 42000, France
CHU Tours
RECRUITING

Tours, 37000, France
Cochin Hospital
RECRUITING

Paris, 75014, France
Henry Mondor hospital
RECRUITING

Créteil, 94000, France
Hopital L'Archet 1
RECRUITING

Nice, 06000, France
Hospital Croix St Simon
NOT_YET_RECRUITING

Paris, 75020, France
Hospital Pasteur - CHU Nice
RECRUITING

Nice, 06000, France
Hôpital Nord
RECRUITING

Marseille, 13015, France
Hôpital Sud
RECRUITING

Rennes, 35200, France
Hôpital de la Cavale Blanche
RECRUITING

Brest, 29200, France
Hôpitaux de Barbois
RECRUITING

Vandœuvre-lès-Nancy, 54500, France
La Pitié-Salpêtrière
RECRUITING

Paris, 75013, France
La Pitié-Salpêtrière
RECRUITING

Paris, 75013, France
La Timone Hospital
RECRUITING

Marseille, 13385, France
La Timone Hospital
RECRUITING

Marseille, 13385, France
Nouvel Hospital Civil
RECRUITING

Strasbourg, 67000, France
Rangueil Hospital
RECRUITING

Toulouse, 31400, France
Robert Debré Hospital
RECRUITING

Reims, 51100, France
Robert Schuman Hospital
RECRUITING

Metz, 57000, France
Saint Antoine Hospital
NOT_YET_RECRUITING

Paris, 75012, France

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