Simple thigh squeezes could be key to knee pain relief
NCT ID NCT07198204
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether holding a simple thigh muscle contraction for 5, 10, or 20 seconds best improves strength, pain, and daily function in people with knee osteoarthritis. 127 adults aged 40-65 with mild to moderate knee arthritis took part. All also received ultrasound and TENS therapy. The goal is to find the simplest, most effective exercise duration to help manage symptoms.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- isometric quadriceps exercises
- What this could lead to
- If it works, this could help identify the best exercise duration to reduce pain and improve function in people with knee osteoarthritis.
- What could go wrong
- This is a small, completed trial with no blinding, so results may be biased. The exercises are simple and low-risk, but benefits may not apply to everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sphynix University
Asyut, Assuit, 71511, Egypt
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