Gentler myeloma combo aims to help frail patients fight relapse

NCT ID NCT05911321

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests a three-drug combination (isatuximab, pomalidomide, and dexamethasone) at lower-than-standard doses in people with multiple myeloma that has returned or not responded to treatment. The goal is to see if the lower doses are both safe and effective for patients who are more vulnerable to side effects due to age or other health problems. About 6 participants will receive the treatment, and researchers will measure how many achieve a meaningful reduction in cancer.

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Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist Medical Center

    Winston-Salem, North Carolina, 27157, United States

  • Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27514, United States

Conditions

Explore the condition pages connected to this study.