REFRACTORY
Clinical trials for REFRACTORY explained in plain language.
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Brain tumor virus therapy tested in kids and young adults
Disease control Recruiting nowThis phase 2 trial tests whether a single injection of DNX-2401, a virus designed to kill cancer cells, can shrink or stabilize recurrent high-grade brain tumors in 39 children and young adults. Participants receive the virus directly into the tumor during a biopsy procedure. The…
Matched conditions: REFRACTORY
Phase: PHASE2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Engineered immune cells take on lupus in first human trial
Disease control Recruiting nowThis early-phase study tests a new treatment called MC-1-50 for adults with severe lupus that hasn't responded to standard therapies. The treatment uses a patient's own immune cells, modified to target and destroy faulty B cells that drive the disease. The main goals are to check…
Matched conditions: REFRACTORY
Phase: PHASE1 • Sponsor: Chongqing Precision Biotech Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Laser breakthrough? new trial aims to save sight in diabetic patients
Disease control Recruiting nowThis study tests a micropulse laser for diabetic macular edema, a condition causing vision loss in people with diabetes. Fifty participants with initial or stubborn swelling will receive the laser treatment. Researchers will measure changes in vision and retinal thickness to see …
Matched conditions: REFRACTORY
Sponsor: The General Authority for Teaching Hospitals and Institutes • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New CAR-T therapy aims to tackle Hard-to-Treat hodgkin lymphoma
Disease control Recruiting nowThis study tests a new type of immunotherapy called CAR-T cells, which are specially engineered to recognize and attack CD30, a protein found on Hodgkin lymphoma cells. The trial enrolls up to 31 adults whose cancer has returned or not responded to standard treatments. Participan…
Matched conditions: REFRACTORY
Phase: PHASE1, PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Florida cancer patients get AI-Powered personalized treatment plans in new study
Knowledge-focused Recruiting nowThis study is testing whether a new tool called xDRIVE, which combines artificial intelligence and tumor profiling, can quickly suggest personalized treatment options for cancer patients in Florida whose cancer has come back or not responded to standard treatments. The goal is to…
Matched conditions: REFRACTORY
Phase: NA • Sponsor: First Ascent Biomedical Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC