REFRACTORY
Clinical trials for REFRACTORY explained in plain language.
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New hope for refractory lymphoma: tailored drug cocktail targets resistant cancer
Disease control Not yet recruitingThis study tests a new approach for people with a type of lymphoma (PTCL) that did not respond to initial chemotherapy. Doctors will use genetic testing of the tumor to choose a personalized combination of drugs, including an experimental drug called zeprumetostat. The goal is to…
Matched conditions: REFRACTORY
Phase: PHASE1, PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New hope for tough anemia: daratumumab trial launches
Disease control Not yet recruitingThis study tests daratumumab, a drug that targets certain immune cells, in 37 people with aplastic anemia that hasn't improved with standard treatments. The first part checks safety and the right dose, and the second part looks at whether it can improve blood cell counts. The goa…
Matched conditions: REFRACTORY
Phase: PHASE1, PHASE2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Tube in the bowel offers hope for stubborn constipation
Knowledge-focused Not yet recruitingThis study follows 80 adults who had a tube placed into their bowel (called a percutaneous endoscopic caecostomy, or PEC) to treat severe chronic constipation that didn't improve with standard treatments. Researchers will check long-term quality of life and how well the tube work…
Matched conditions: REFRACTORY
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:23 UTC