REFRACTORY
Clinical trials for REFRACTORY explained in plain language.
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New hope for patients with bone marrow disease that Won't respond to treatment
Disease control Not yet recruitingThis early-stage study is testing a drug called daratumumab in adults with a severe form of aplastic anemia that has not responded to or has come back after standard treatments. The main goals are to find a safe dose and see if the drug can help improve patients' blood counts. Th…
Matched conditions: REFRACTORY
Phase: PHASE1, PHASE2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Virus injected into brain to fight deadly childhood tumors
Disease control Not yet recruitingThis study is testing a new treatment for aggressive brain tumors that have come back or stopped responding to standard treatments in children and young adults. It involves a single injection of a modified virus (DNX-2401) directly into the tumor during a biopsy procedure. The ma…
Matched conditions: REFRACTORY
Phase: PHASE2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Years later: does a colon tube truly help severe constipation?
Symptom relief Not yet recruitingThis study is checking on patients years after they had a special tube placed into their colon to help with severe, treatment-resistant constipation. Researchers will call 80 patients who had the procedure at a French hospital to ask about their quality of life, symptoms, and any…
Matched conditions: REFRACTORY
Sponsor: Nantes University Hospital • Aim: Symptom relief
Last updated Mar 17, 2026 13:09 UTC