REFRACTORY
Clinical trials for REFRACTORY explained in plain language.
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New hope for refractory lymphoma: tailored drug cocktail targets resistant cancer
Disease control Not yet recruitingThis study tests a personalized combination of drugs for people with a type of lymphoma (PTCL) that did not respond to initial chemotherapy. Researchers will use genetic information from each patient's tumor to select the best drug combination, including an experimental drug call…
Matched conditions: REFRACTORY
Phase: PHASE1, PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New hope for rare blood disorder: daratumumab trial targets refractory aplastic anemia
Disease control Not yet recruitingThis study tests a drug called daratumumab in people with aplastic anemia that hasn't improved with standard treatments. The goal is to see if it is safe and can help the body make more blood cells. About 37 participants will receive multiple doses, and researchers will check for…
Matched conditions: REFRACTORY
Phase: PHASE1, PHASE2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Virus injected into brain tumors shows promise for kids with no other options
Disease control Not yet recruitingThis study tests a treatment called DNX-2401, a virus that is injected directly into brain tumors to kill cancer cells. It is for children and young adults (up to age 39) whose high-grade brain tumors have come back or not responded to standard treatments. The goal is to see if t…
Matched conditions: REFRACTORY
Phase: PHASE2 • Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New study checks if a stomach tube helps severe constipation in the long run
Symptom relief Not yet recruitingThis study follows 80 adults who had a procedure called percutaneous endoscopic caecostomy (PEC) for severe chronic constipation that didn't get better with standard treatments. Researchers will check long-term quality of life and how well the procedure is tolerated by phone inte…
Matched conditions: REFRACTORY
Sponsor: Nantes University Hospital • Aim: Symptom relief
Last updated May 06, 2026 16:03 UTC