New combo therapy shows promise for tough head and neck cancers
NCT ID NCT05172258
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times
Summary
This study tests whether adding the drug ipatasertib to standard immunotherapy (pembrolizumab) can help control recurrent or metastatic head and neck cancer better than immunotherapy alone. About 52 adults with incurable squamous cell carcinoma of the head and neck will take part. The goal is to see if the combination slows cancer growth and is safe.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Antelope Valley
Lancaster, California, 93534, United States
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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City of Hope at Irvine Lennar
Irvine, California, 92618, United States
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Keck Medicine of USC Koreatown
Los Angeles, California, 90020, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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MedStar Georgetown University Hospital
Washington D.C., District of Columbia, 20007, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Einstein Campus
The Bronx, New York, 10461, United States
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NYP/Weill Cornell Medical Center
New York, New York, 10065, United States
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NYU Langone Hospital - Long Island
Mineola, New York, 11501, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Stanford Cancer Institute Palo Alto
Palo Alto, California, 94304, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536, United States
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University of Texas Medical Branch
Galveston, Texas, 77555-0565, United States
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University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin, 53718, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
Conditions
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