RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New drug combo aims to supercharge immune system to fight cancer before surgery
Disease control Recruiting nowThis study is testing if adding a new immune-boosting drug (CDX-1140) to an existing immunotherapy (cemiplimab) works better before surgery for advanced head and neck cancer. The goal is to shrink the tumor more effectively, which could lead to less extensive surgery. About 44 pa…
Matched conditions: RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Cholesterol drug may boost cancer treatment in new trial
Disease control Recruiting nowThis study is testing whether adding the common cholesterol-lowering drug lovastatin to the immunotherapy drug pembrolizumab can better control head and neck cancer that has returned or spread. Researchers believe lovastatin may make cancer cells more vulnerable to the immune sys…
Matched conditions: RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New hope for Tough-to-Treat head & neck cancer recurrence
Disease control Recruiting nowThis study is for people whose head and neck cancer has come back after initial treatment. After surgery, it compares a newer immunotherapy drug (pembrolizumab) to the standard combination of chemotherapy and radiation. The main goal is to see if the immunotherapy helps patients …
Matched conditions: RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Doctors test custom vaccine to fight returning head and neck cancer
Disease control Recruiting nowThis early-stage study is testing a personalized vaccine made from a patient's own tumor cells. It aims to see if the vaccine, given alone or with an immunotherapy drug (pembrolizumab), is safe and can help the immune system fight advanced head and neck cancer that has returned o…
Matched conditions: RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New hope for Tough-to-Treat head and neck cancers: can a drug duo outperform the standard?
Disease control Recruiting nowThis study is for people with advanced head and neck cancer that has returned or spread and has stopped responding to standard platinum-based chemotherapy. It aims to see if combining two immunotherapy drugs (pembrolizumab and cetuximab) helps patients live longer than using pemb…
Matched conditions: RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Scientists hunt for hidden cancer clues in spit and blood
Knowledge-focused Recruiting nowThis study aims to find biological markers in blood and saliva that can tell doctors when a person has HPV-related throat cancer and when they don't. Researchers will collect samples and review medical records from 440 adults with or at risk for head and neck cancers. The goal is…
Matched conditions: RECURRENT OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC