New drug targets AKT mutations in Hard-to-Treat cancers

NCT ID NCT06400251

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests a drug called ipatasertib in people with advanced cancers (like lymphoma or solid tumors) that have a specific genetic change called an AKT mutation. The drug works by blocking a protein that helps cancer cells grow. The main goal is to see if the drug can shrink tumors or stop them from growing. About 35 adults are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.