Brain cancer breakthrough? trial adds radiation during surgery to fight glioblastoma
NCT ID NCT02685605
First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 38 times
Summary
This phase 3 trial tests whether giving a dose of radiation directly to the tumor site during surgery (intraoperative radiotherapy) can help people with a newly diagnosed aggressive brain cancer called glioblastoma live longer without their cancer growing. The study involves 314 adults aged 18 to 80 who are healthy enough for surgery. The goal is to see if adding this extra radiation to the usual treatment plan improves outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Barrow Neurological Institute (SJHMC)
Phoenix, Arizona, 85013, United States
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Beijing Tian Tan Hospital, Capital Medical University
Beijing, 100050, China
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Catalan Institute of Oncology (ICO)
Barcelona, 08908, Spain
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Charité - Universitätsmedizin
Berlin, 13353, Germany
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Gangnam Severance Hospital, Yonsei University College of Medicine
Seoul, 06273, South Korea
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Helios University Hospital Wuppertal
Wuppertal, 42283, Germany
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Hospital Alemão Oswaldo Cruz
São Paulo, 01323-020, Brazil
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Hospital Reina Sofia
Córdoba, Spain
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Klinikum Stuttgart
Stuttgart, 70174, Germany
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Lenox Hill Hospital, Hofstra Northwell School of Medicine
New York, New York, 10028, United States
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Long Island Jewish Medical Center, North Shore University Hospital
Lake Success, New York, 11042, United States
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Montreal Neurological Institute and Hospital
Montreal, Quebec, H3A 2B4, Canada
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St. Georg Hospital
Leipzig, Germany
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Stritch School of Medicine Loyola University
Maywood, Illinois, 60153, United States
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Technical University of Munich (TUM), Department of Radiation Oncology
Munich, 81675, Germany
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The London Clinic
London, W1G 6BW, United Kingdom
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University Hospital Augsburg
Augsburg, 86156, Germany
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University Hospital Mannheim
Mannheim, 68167, Germany
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West Virginia University
Morgantown, West Virginia, 26506-9260, United States
Conditions
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