New molecular test could spot heart transplant rejection faster
NCT ID NCT02670408
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to see if a new molecular test can better detect rejection in heart transplant patients compared to standard biopsy analysis. Researchers will collect extra biopsy samples from 900 participants and analyze them using the Molecular Microscope Diagnostic System. The goal is to create a more accurate and timely tool for diagnosing rejection, potentially improving long-term outcomes for transplant recipients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a more accurate and faster way to detect rejection in heart transplant patients, potentially improving their care.
What could go wrong
This is an observational study, not a treatment trial. The new test may not prove more useful than current methods, and results may not change patient outcomes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Advanced Heart Failure Transplant Unit
COMPLETEDA Coruña, Spain
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Alberta Transplant Applied Genomics Center, University of Alberta
RECRUITINGEdmonton, Alberta, T6G 2E1, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Annette C. and Harold C. Simmons Transplant Institute, BaylorScott&White Research Institute
COMPLETEDDallas, Texas, 75246, United States
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Cardiac Transplantation Laboratory, The Victor Chang Cardiac Research Institute
RECRUITINGDarlinghurst, NSW 2010, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Cardiovascular Medicine, University of Utah Health
COMPLETEDSalt Lake City, Utah, 84132, United States
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Cedars-Sinai Heart Institute
COMPLETEDLos Angeles, California, 90048, United States
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Department of Cardiac Surgery, Medical University of Vienna
RECRUITINGVienna, A-1090, Austria
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Division of Cardiology, University of Alberta
COMPLETEDEdmonton, Alberta, T6G 2R7, Canada
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Heart Failure and Heart Transplant Unit, University of Bologna
COMPLETEDBologna, 40138, Italy
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Institute for Clinical and Experimental Medicine - IKEM
RECRUITINGPrague, 14021, Czechia
Contact Email: •••••@•••••
Contact
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Service de Néphrologie-Dialyse Adultes , Hôpital Necker-Enfants Malades
COMPLETEDParis, 75015, France
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UCLA Medical Centre
COMPLETEDLos Angeles, California, 90024, United States
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Virginia Commonwealth University, Division of Cardiology
COMPLETEDRichmond, Virginia, 23298, United States