New shot could cut stroke risk for High-Risk patients

NCT ID NCT07341958

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a drug called Tafolecimab to standard cholesterol-lowering therapy can reduce the risk of another stroke in people who have had a recent stroke or mini-stroke and have high levels of Lp(a), a type of fat in the blood. About 242 participants will receive either the drug or a placebo shot every two weeks for 90 days. The main goal is to see if Lp(a) levels drop and if fewer strokes occur.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tafolecimab (a PCSK9 inhibitor drug given as a shot every two weeks)

What this could lead to

If it works, this could point toward a new way to reduce stroke risk in people with high Lp(a) levels who are already on standard cholesterol-lowering therapy.

What could go wrong

This is a small, early-stage trial (242 participants) testing a short-term treatment (90 days). The results may not apply to everyone, and the drug could have side effects or fail to reduce stroke recurrence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIGH-RISK TRANSIENT ISCHEMIC ATTACK are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atherosclerosis ischemic stroke transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hopital, Capital Medical University

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••