Could a single dose of infliximab speed kidney recovery in immunotherapy patients?
NCT ID NCT07683975
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study tests whether adding a single dose of infliximab to a short course of prednisone helps people recover kidney function faster after immunotherapy-related acute kidney injury. Participants receive either the combination or standard prednisone alone. The goal is to see if the combination improves recovery rates within 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Infliximab and prednisone
- What this could lead to
- If it works, this could point toward a faster, more effective treatment for immunotherapy-related kidney injury, potentially reducing the need for long-term steroids.
- What could go wrong
- This is a small pilot study, so results may not be conclusive. Infliximab carries risks like infection and allergic reactions, and the combination may not outperform standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
Contact Email: •••••@•••••
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
Contact Email: •••••@•••••
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Contact Email: •••••@•••••
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