Which dialysis method works best for ICU kidney failure? a Head-to-Head test

This trial compares two ways of filtering blood in critically ill patients with severe acute kidney injury: intermittent hemodialysis (done in sessions) and continuous renal replacement therapy (done non-stop). The goal is to see if the intermittent method is just as good as the continuous one in preventing death, lasting kidney damage, or the need for ongoing dialysis at 90 days. About 1,000 ICU adults on breathing support or blood pressure medication will be randomly assigned to one of the two methods. The study aims to help doctors choose the best dialysis approach for these very sick patients.