Can an immune boost keep myeloma patients Infection-Free on powerful new drugs?
NCT ID NCT06980480
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 3 trial tests whether giving immune globulin (IGI) regularly can prevent serious infections in adults with multiple myeloma who are receiving a bispecific antibody therapy. About 183 participants will be randomly assigned to get IGI right away for 12 months or only after a serious infection occurs. The study aims to see if early, routine use of IGI reduces the number of serious infections compared to waiting until an infection happens.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Immune globulin infusion (10%)
What this could lead to
If it works, this could provide a standard way to prevent serious infections in multiple myeloma patients on bispecific antibody therapy.
What could go wrong
This is a Phase 3 trial, but it only compares two prevention strategies, not a placebo. Results may not apply to all patients or settings.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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A O Krankenhaus der Elisabethinen
RECRUITINGLinz, 4020, Austria
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Aidport sp. z o.o.
RECRUITINGSkorzewo, 60-185, Poland
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Alexandra General Hospital of Athens
RECRUITINGAthens, 105 57, Greece
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Amsterdam University Medical Center (Amsterdam UMC)
RECRUITINGAmsterdam, 1019PE, Netherlands
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Azienda Ospedaliero-Universitaria delle Marche; SOD Clinica Medica
RECRUITINGTorrette, 60126, Italy
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Cardiff & Vale University Health Board
RECRUITINGCardiff, South Glamorgan, CF14 4XU, United Kingdom
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Centre Hospitalier de l'Universite de Montreal
RECRUITINGMontreal, Quebec, H2X 0A9, Canada
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Chao Family Comprehensive Cancer Center UCI
RECRUITINGOrange, California, 92868, United States
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County Hospital (Stafford Hospital)
RECRUITINGStafford, ST16 3SA, United Kingdom
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Fiona Stanley Hospital
RECRUITINGMurdoch, Western Australia, 6150, Australia
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Gloucestershire Royal Hospital
RECRUITINGGloucester, Gloucestershire, GL1 3NN, United Kingdom
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Henry Ford Health System
RECRUITINGDetroit, Michigan, 48202, United States
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Hospital Costa Del Sol
RECRUITINGMarbella, 29603, Spain
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Hospital Universitari Son Espases (HUSE) (Hospital Universitario Son Dureta) (HUSD)
RECRUITINGPalma de Mallorca, 7120, Spain
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Hospital Universitari i Politecnic La Fe
RECRUITINGValencia, 46026, Spain
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Infirmary Health - Diagnostic & Medical Clinic (DMC)
RECRUITINGMobile, Alabama, 36604, United States
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Krankenhaus der Barmherzigen Schwestern Wien
RECRUITINGVienna, 1060, Austria
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New York Oncology Hematology
RECRUITINGAlbany, New York, 12208, United States
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Odense Universitetshospital
RECRUITINGOdense, 5000, Denmark
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Somogy Megyei Kaposi Mor Oktato Korhaz
RECRUITINGKaposvár, 7400, Hungary
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St George Private Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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St. Antonius Ziekenhuis
RECRUITINGNieuwegein, 3435, Netherlands
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Townsville Hospital
RECRUITINGDouglas, Queensland, 4814, Australia
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Universitaetsklinikum St. Poelten
RECRUITINGSankt Pölten, 3100, Austria
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University of Kansas
RECRUITINGWestwood, Kansas, 66205, United States
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University of Maryland | Greenebaum Cancer Center
RECRUITINGBaltimore, Maryland, 21201, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63141, United States
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Western Health - Sunshine Hospital
RECRUITINGSt Albans, Victoria, 3021, Australia
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