New pill shows promise for inherited kidney disease

NCT ID NCT06794996

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 25 times

Summary

This study tests an experimental drug called inaxaplin in 42 people with a genetic form of kidney disease linked to the APOL1 gene. The goal is to see if the drug can reduce protein in the urine, a sign of kidney damage, and slow disease progression. Participants must have a specific APOL1 gene pattern and moderate to advanced kidney function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CTR Oakwater, LLC

    Orlando, Florida, 32806, United States

  • Carolina Nephrology, PA

    Spartanburg, South Carolina, 29306, United States

  • Columbia Nephrology Associates, PA

    Columbia, South Carolina, 29203, United States

  • DaVita Kidney Care - Las Vegas

    Las Vegas, Nevada, 89107, United States

  • Dallas Nephrology Associates - Dallas Landry Office

    Dallas, Texas, 75246, United States

  • Dallas Renal Group - 1

    Dallas, Texas, 75237, United States

  • Dallas Renal Group - 2

    Dallas, Texas, 75230, United States

  • Duke University Hospital - Children's Health Center

    Durham, North Carolina, 27710, United States

  • Eastern Nephrology Associates - New Bern Office

    New Bern, North Carolina, 28562, United States

  • Foundation for Sickle Cell Disease Research, LLC

    Hollywood, Florida, 33023, United States

  • Georgia Nephrology

    Lawrenceville, Georgia, 30046, United States

  • Georgia Nephrology - Decatur

    Decatur, Georgia, 30030, United States

  • Javara Inc. /Privia Medical Group Georgia, LLC - Savannah

    Savannah, Georgia, 31406, United States

  • Javara Inc./Privia Medical Group Georgia, LLC - Fayetteville

    Fayetteville, Georgia, 30214, United States

  • Javara Inc./Privia Medical Group, LLC MidAtlantic-Silver Spring, MD

    Silver Spring, Maryland, 20901, United States

  • LCMC Health

    Metairie, Louisiana, 70006, United States

  • Lewis Katz School of Medicine at Temple University - Section of Nephrology

    Philadelphia, Pennsylvania, 19140, United States

  • NYC Health + Hospital/Harlem

    New York, New York, 10037, United States

  • Nephrology Associates, P.C.

    Columbus, Mississippi, 39705, United States

  • Nephrology Consultants, LLC

    Huntsville, Alabama, 35805, United States

  • Nephrology and Hypertension Associates, LTD

    Tupelo, Mississippi, 38801, United States

  • North Carolina Nephrology P.A. - Cary Office

    Cary, North Carolina, 27511, United States

  • Northwest Louisiana Nephrology, LLC - Shreveport

    Shreveport, Louisiana, 71101, United States

  • Ochsner Medical Center - New Orleans - Nephrology

    New Orleans, Louisiana, 70121, United States

  • Prolato Clinical Research Center

    Houston, Texas, 77054, United States

  • Renal Associates of Baton Rouge

    Baton Rouge, Louisiana, 70808, United States

  • Renal Associates, LLC

    Columbus, Georgia, 31904, United States

  • Rutgers Doctors Office Center

    Newark, New Jersey, 07103, United States

  • Saint Michael's Medical Center - Peter Ho Memorial Clinic

    Newark, New Jersey, 07102, United States

  • Schiff Center for Liver Diseases

    Miami, Florida, 33136, United States

  • Scott Research, Inc.

    Laurelton, New York, 11413, United States

  • South Florida Research Institute

    Lauderdale Lakes, Florida, 33313, United States

  • Tks Research, P.L.L.C.

    Norfolk, Virginia, 23504, United States

  • UNC Clinical and Translational Research Center

    Chapel Hill, North Carolina, 27599-7155, United States

  • UTSW Medical Center - Nephrology

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.