Blood test may flag hidden kidney disease risk before damage is done

NCT ID NCT06839833

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This study tests a blood-based genetic test designed to identify people who carry two copies of high-risk APOL1 gene variants, which are linked to a type of kidney disease. Around 2,000 participants who are already being considered for a separate treatment trial will provide a blood sample for the test. The goal is to see if the test can reliably find those who might be eligible for a new experimental therapy targeting APOL1-mediated kidney disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
APOL1 genotyping test (a diagnostic blood test to detect high-risk APOL1 gene variants)
What this could lead to
If the test works well, it could help identify people who may benefit from a new targeted therapy for APOL1-related kidney disease.
What could go wrong
This is an early-stage diagnostic study, not a treatment trial. The test may not be accurate enough in real-world use, and even if it is, the linked treatment is still being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Almac Diagnostic Services LLC

    RECRUITING

    Durham, North Carolina, 27704, United States

    Contact Email: •••••@•••••

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