New hope for cancer patients: drug may shield kidneys from treatment side effect

NCT ID NCT07224776

First seen Nov 06, 2025 · Last updated May 13, 2026 · Updated 22 times

Summary

This early study tests if the drug sparsentan can reduce high levels of protein in the urine (a sign of kidney damage) in 20 cancer patients receiving VEGF inhibitor therapy. The goal is to see if sparsentan can help protect kidney function without interrupting cancer treatment. Participants will take sparsentan for 8 weeks, and researchers will measure changes in protein levels and track any treatment interruptions.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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