New MS pill aims to slash relapses in major trial
NCT ID NCT05201638
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 study tests an oral medication called IMU-838 against a placebo in about 1,100 adults with relapsing multiple sclerosis (MS). The goal is to see if the drug can reduce the number of relapses and new brain lesions over 72 weeks. Participants must be 18-55 years old with active disease, defined by recent relapses.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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"University Clinic" of Dnipro State Medical University, Department of Neurology
Dnipro, 49038, Ukraine
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1 Private Clinic Medical Center
Kyiv, Ukraine
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19 Mayis University Medical Faculty Hospital Health Application and Research Center
Samsun, 55200, Turkey (Türkiye)
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5 City Clin Hospital
Lviv, 79013, Ukraine
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Adana Baskent Hospital
Adana, 01250, Turkey (Türkiye)
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All India Institute of Medical Sciences
New Delhi, 110029, India
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Aria Clinic SRL
Sibiu, 550052, Romania
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Astra Clinic
Tallinn, Estonia
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Bezmialem Vakif University Hospital
Istanbul, 34093, Turkey (Türkiye)
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Cantonal Hospital Bihac Dr. Irfan Ljubijankic
Bihać, 77000, Bosnia and Herzegovina
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Centrum Med. Ibismed
Zabrze, Poland
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Centrum Medyczne NeuroProtect
Warsaw, 01684, Poland
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Chernihiv City Hospital 4
Chernihiv, Ukraine
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City Clinical Hospital 2
Rivne, Ukraine
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Clubul Sanatatii SRL
Campulung Muscel, 115100, Romania
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Communal Non-Commercial Medical Enterprise "O.T.Bohayevskyi Kremenchuk City Hospital #1
Kremenchuk, 39623, Ukraine
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Communal institution "City Clinical Hospital №3" of Poltava City Council
Poltava, 36000, Ukraine
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Communal noncommercial enterprise "First Cherkasy City Hospital"
Cherkasy, 18009, Ukraine
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DKS PGI
Raipur, 492001, India
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Dnipro City Hospital 6
Dnipro, Ukraine
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Dopomoga Plus medical center
Kyiv, Ukraine
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Dr Ram Manohar Lohia Institute of Medical Sciences
Lucknow, 226010, India
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Erebouni Medical Center
Yerevan, 0087, Armenia
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Fortis Memorial Research Institute
Gurugramam, 122002, India
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FutureMeds Warszawa Centrum
Warsaw, Poland
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GB Pant Institute of Postgraduate Medical Education and Research
New Delhi, 110056, India
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General Hospital Leskovac
Leskovac, 16000, Serbia
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General Hospital Uzice
Užice, 31000, Serbia
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Haydar Pasa Num. EAH
Istanbul, Turkey (Türkiye)
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Healthcare Innovations
Coral Springs, Florida, 33067, United States
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Heratsi Hospital Complex 1
Yerevan, 0025, Armenia
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Hospital Nacional Dos de Mayo
Lima, 15003, Peru
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Hsptl Sveti Vracevi
Novi Kneževac, Serbia
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Indywidualna Praktyka Lekarska prof. Konrad Rejdak
Lublin, 20-410, Poland
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Instytut Zdrowia Boczarska
Oświęcim, 32-600, Poland
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Klinicko Bolnicki centar Zemun
Zemun, 11080, Serbia
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Klinicko bolnicki centar Dr Dragisa Misovic - Dedinje
Belgrade, 11000, Serbia
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Klinicko bolnicki centar Zvezdara
Belgrade, 11000, Serbia
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Kocaeli University Research and Application Hospital
Kocaeli, 41000, Turkey (Türkiye)
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Kutahya Uni Evliya Celebi Hspt
Kütahya, 43040, Turkey (Türkiye)
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Lviv Regional Central Hospital
Lviv, 79010, Ukraine
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MS Diagnosis Treatment Center
Cherkasy, Ukraine
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Manisa Celal Bayar University Hafsa Sultan Hospital
Manisa, 45030, Turkey (Türkiye)
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Municipal Institution "Dnipropetrovsk Regional Rehabilitation Hospital" of Dnipropetrovsk Regional Council"
Dnipro, 49000, Ukraine
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NZOZ Hertmanowskiej
Plewiska, 62-064, Poland
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NZOZ Neuro-Kard
Poznan, 61-853, Poland
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NZOZ Neuromed
Lublin, 20-064, Poland
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NZOZ Novo-Med
Katowice, 40-584, Poland
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NZOZ Wielospecjalistyczna Poradnia Lekarska "Synapsis"
Katowice, 40123, Poland
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Namik Kemal Uni Hospital
Tekirdağ, 59100, Turkey (Türkiye)
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Neuro of Central Florida
Altamonte Springs, Florida, 32714, United States
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Neuro-Medic Janusz Zbrojkiewicz
Katowice, 40686, Poland
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Opsta bolnica Djordje Jovanovic Zrenjanin
Zrenjanin, 23000, Serbia
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Polakulath Narayanan Renai Medicity MSSH
Kochi, 682025, India
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Post-Graduation Institute of Medical Education and Research (PGIMER)
Chandigarh, 160012, India
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Royal Hallamshire Hospital
Sheffield, United Kingdom
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SRI Guru Ram Das Institute of Medical Sciences and Research
Punjābi Bāgh, 143006, India
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Saint Gregory the Illuminator Medical Center
Yerevan, 0056, Armenia
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Sakarya Egitim ve Arastirma Hast
Sakarya, 54100, Turkey (Türkiye)
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Salutem
Vinnytsia, 21018, Ukraine
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Sancaktepe Sehit Prof.Dr. Ilhan Varank Training and Research Hospital
Istanbul, 34785, Turkey (Türkiye)
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Spitalul clinic CF Constanta
Constanța, 900123, Romania
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State Institution "National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine
Kyiv, 03115, Ukraine
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Sumy Reg Clinical Hospital
Sumy, Ukraine
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T.C. Ministry of Health Istanbul Haseki Training and Research Hospital
Istanbul, 34250, Turkey (Türkiye)
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UCC of Rep of Srpska
Banja Luka, Bosnia and Herzegovina
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Ukrainian State Research Institute of Medico-Social Problems of Disability
Dnipro, 49027, Ukraine
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Uludag University Hospital
Bursa, 16059, Turkey (Türkiye)
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University Clinical Center Sarajevo
Sarajevo, 71000, Bosnia and Herzegovina
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University Clinical Center Tuzla
Tuzla, 75000, Bosnia and Herzegovina
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University Clinical Center of Sarajevo
Sarajevo, 71000, Bosnia and Herzegovina
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University Hospital Muenster, Institute Translational Neurology dept. Neurology
Münster, 48149, Germany
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Univerzitetski Klinicki centar Kragujevac
Kragujevac, 34000, Serbia
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Univerzitetski Klinicki centar Nis
Niš, 18000, Serbia
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Vojnomedicinska akademija
Belgrade, 11000, Serbia
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Volyn Reg Clin Hospital
Lutsk, 43005, Ukraine
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a gentle electric zap to the brain restore memory in MS?
- Brain scans may reveal how MS drug affects mental fatigue
- Brain scans could reveal which MS drugs fight mental exhaustion
- Brain shrinkage as a crystal ball for MS progression?
- Can a Once-a-Month shot tame MS relapses?
- Can MS treatments protect the mind as well as the body?