Talking it out: study tests if a phone call can tame inherited high cholesterol

NCT ID NCT05238519

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a motivational interview—a 20-40 minute phone or video chat—can help people with familial hypercholesterolemia (FH) get their cholesterol checked and talk to family about screening. About 300 people with suspected or confirmed FH will be randomly assigned to usual care or the interview. The goal is to improve awareness and management of this genetic condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

motivational interview

What this could lead to

If successful, this could show that a simple conversation helps more people get diagnosed and manage their cholesterol better.

What could go wrong

This is a behavioral study, not a drug trial, so it won't directly lower cholesterol. Results depend on people's willingness to change habits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

familial hypercholesterolemia hereditary disease Hypercholesterolemia hyperlipidemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aspirus St. Luke's Hospital

    Duluth, Minnesota, 55805, United States

  • Essentia Health

    Duluth, Minnesota, 55805, United States