Talking it out: study tests if a phone call can tame inherited high cholesterol

NCT ID NCT05238519

Ongoing Knowledge-focused Sponsor: Essentia Health Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a motivational interview—a 20-40 minute phone or video chat—can help people with familial hypercholesterolemia (FH) get their cholesterol checked and talk to family about screening. About 300 people with suspected or confirmed FH will be randomly assigned to usual care or the interview. The goal is to improve awareness and management of this genetic condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: motivational interview
What this could lead to: If successful, this could show that a simple conversation helps more people get diagnosed and manage their cholesterol better.
What could go wrong: This is a behavioral study, not a drug trial, so it won't directly lower cholesterol. Results depend on people's willingness to change habits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

familial hypercholesterolemia hereditary disease Hypercholesterolemia hyperlipidemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOLESTEROL, ELEVATED FAMILIAL HYPERCHOLESTEROLEMIA GENETIC DISEASE

Contacts and locations

Locations

Aspirus St. Luke's Hospital

Duluth, Minnesota, 55805, United States
Essentia Health

Duluth, Minnesota, 55805, United States

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