Experimental liver shot aims to wake up immune system against colorectal cancer

NCT ID NCT07172282

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing whether a drug called Nelitolimod, given directly into the liver through a special catheter, can safely boost the immune system in 10 people with colorectal cancer that has spread to the liver. Participants will receive the drug three times before their planned liver surgery. The main goal is to see if this approach is feasible and safe, not yet to prove it works against the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nelitolimod

What this could lead to

If this works, it could point toward a new way to boost the immune system against colorectal cancer that has spread to the liver, potentially making surgery more effective.

What could go wrong

This is a very early, small study with only 10 people. It is designed mainly to check safety and feasibility, not to prove the treatment works. The drug may not produce a meaningful immune response or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • RJ Zuckerberg

    RECRUITING

    Lake Success, New York, 11042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••