Freezing fat to breathe better? new study probes how cryotherapy helps sleep apnea

NCT ID NCT06434558

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This observational study follows 10 adults with obstructive sleep apnea who are already receiving a cryotherapy treatment (the Cryosa Procedure). Researchers will use MRI and ultrasound before and after treatment to measure fat in the throat and nerve activity. The goal is to find out which patients respond best and how the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cryosa Procedure (cryotherapy)
What this could lead to: If successful, this could help doctors predict which sleep apnea patients will benefit most from the Cryosa Procedure.
What could go wrong: This is a very small observational study (10 people) that does not test the procedure itself. It only looks for patterns, so results may not apply widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSTRUCTIVE SLEEP APNEA OF ADULT

Contacts and locations

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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