Brain scans may reveal how lewy body dementia progresses

NCT ID NCT03582488

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Kejal Kantarci Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 135 people with Lewy body dementia over up to 5 years, using special PET scans to measure brain changes linked to memory and thinking decline. Researchers hope to find imaging markers that show how the disease progresses. Participants will have regular tests and scans, but no new treatment is being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 18F-Flortaucipir and Pittsburgh Compound-B (PET imaging radioligands)
What this could lead to: If successful, this could help doctors predict how Lewy body dementia will progress and guide future treatment trials.
What could go wrong: This is an observational imaging study, not a treatment trial. It may not directly benefit participants, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LEWY BODY DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Lewy body dementia Lewy Body Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LEWY BODY DISEASE

Contacts and locations

Locations

Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.