Brain scans may reveal how lewy body dementia progresses

NCT ID NCT03582488

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Kejal Kantarci Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 135 people with Lewy body dementia over up to 5 years, using special PET scans to measure brain changes linked to memory and thinking decline. Researchers hope to find imaging markers that show how the disease progresses. Participants will have regular tests and scans, but no new treatment is being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-Flortaucipir and Pittsburgh Compound-B (PET imaging radioligands)

What this could lead to

If successful, this could help doctors predict how Lewy body dementia will progress and guide future treatment trials.

What could go wrong

This is an observational imaging study, not a treatment trial. It may not directly benefit participants, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Lewy body dementia Lewy Body Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States