Frozen heart fix: new device targets AFib
NCT ID NCT05416086
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a medical device that freezes small areas of heart tissue to treat atrial fibrillation (AFib) and related irregular heartbeats. The goal was to see if the procedure safely stops abnormal rhythms for at least 12 months. The study enrolled 91 people, but was terminated early, so the full results are not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cryoablation procedure using the iCLAS Cryoablation System
- What this could lead to
- If successful, this could offer a safe and effective way to freeze abnormal heart tissue and restore normal rhythm in people with atrial fibrillation.
- What could go wrong
- The study was terminated early, so results are limited. Cryoablation carries risks like heart tissue damage or blood clots, and the procedure may not prevent future arrhythmias.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Erasmus MC
Rotterdam, Netherlands
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Onze-Lieve-Vrouw Hospital Aalst (OLV)
Aalst, 9300, Belgium
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St. Antonius Ziekenhuis
Nieuwegein, 3435, Netherlands
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Universitatsklinikum Erlangen
Erlangen, 91054, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new freezing balloon tame a fluttering heart as well as the old one?
- Do antiplatelet drugs work the same in patients over 80? a study puts it to the test.
- Can closing a hole in the heart prevent future strokes? a long-term study seeks answers.
- Heart signals may reveal if a common AFib procedure will last
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